Senior Alison Bales fouled out of the game for the first time in her career (103 games).
The Blue Devils played their second straight ranked opponent in a stretch of four straight ranked foes.
Sophomore Abby Waner scored double-figures for the eighth straight game as she totaled 14 points.She also tied a career-high with two blocks.
Duke broke a three-game streak of shooting above 50.0 percent from the field as the Blue Devils shot 43.8 percent.
Vanderbilt became the first team to shoot above 30.0 percent from the field in a contest this season against the Blue Devils (33.3).
Senior Alison Bales registered her fourth straight game with double-figure points as she posted 11 points in the first half.She went on to finish with 16 points.
Senior Lindsey Harding posted double-figure scoring for the fourth time this season and the fourth time out of the last five contests with 15 points.She tied a career high with two three-pointers made on the night.Harding has scored 34 points the last two contests.
Duke had a season-low 12 assists.
Junior Wanisha Smith scored double-figures for the second time this season with a season-high 10 points.She also added seven rebounds and four assists.
With her four blocks on the night, senior Alison Bales moved into 23rd place on the NCAA all-time blocks list with 324. She is now five blocks away from second place and six away from first place on the ACC all-time chart.
For the first time this season, Duke scored under 70 points.
After having only 12 turnovers last game against 19th-ranked Rutgers, Duke had 12 turnovers in the first half and went on finish with a season-high 23 turnovers for the contest.
Freshman Bridgette Mitchell came off the bench in the first half and scored six points, had four rebounds and one steal in five minutes.She finished the game with six points, five rebounds and one steal in eight minutes.
For the first time this season, all 10 players did not play for Duke and all did not score.
Duke forced one shot clock violation in the contest and has now forced nine violations in eight games.
Duke will next host 22nd-ranked Texas on Sunday, Dec. 10 at 1:00 p.m.The contest will be aired live on ESPNU.