Duke maintains its 12 year winning streak in first round NCAA appearances.
The 69 point margin of victory is Duke's highest in NCAA tournament action and is the fifth-highest in NCAA tournament history overall. Duke's previous record for an NCAA tournament game was 52 over Northwestern State on March 21, 2004.
The 27 points scored by Southern is the lowest amount in NCAA Tournament history.
Duke had four players score in double figures for the first time since February 22, 2006 when five players scored in double figures in a 93-51 win over Virginia Tech.
Monique Currie's 19 points on the night ties Chasity Melvin for 12th on the ACC career scoring charts with 2,042 career points.
Lindsey Harding had 18 points on the night, her second consecutive double figure game. Harding also registered two three-pointers, her second performance with two or more threes following a six game streak without a three-point shot.
Duke continues its school record with at least 15 games in a season scoring over 90 points.
After being out-rebounded three of the last four games, Duke grabbed 60 rebounds to Southern's 28.
The rebound margin of 32 is the seventh largest in NCAA tournament history.
Duke's 60 rebounds marks their highest of the year since December 19, 2005 against Ball State (62).
Jessica Foley notched two three-pointers, giving her 169 in her career, and tying her for 23rd place in ACC history with Georgia Tech's Carla Munnion.
Alison Bales' two blocked shots improved on her school record 255 career blocked shots.
Duke ended with a 30 point advantage in the paint (44-14).
Monique Currie's needs only two more assists to make her the first player in ACC history to record over 2,000 points, 800 rebounds, 400 assists and 200 steals in a career.
All 11 of Duke's players saw at least 10 minutes of action, with each player scoring as well.
The game marks the second fewest points (27) and field goals (11) allowed by Duke this season.